| Author
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Topic:
Prepared Food & Cancer |
nick Moderator
Member # 5
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posted October 17, 2005 10:23 PM
"Foods
Causing Cancer" is very interesting.
I found a report
on The National Cancer Institute's site about HCA in prepared
cooked food.
NCI report
I understand the
point you make between cooked meat and how vegetables cause
less cancer.
I also see the point you make about
(endogenous) oxidative radicals being necessary and healthy,
while exogenous radicals are unhealthy.
I totally
understand how antioxidants are 'there' to control the natural
radicals. This makes perfect sense.
I understand that
radicals have an unpaired electron and then steal one from
another molecule thus making that molecule a radical. It's
unbalanced?
"One of the insidious things about free
radicals is that in interacting with other molecules to gain a
stable configuration of electrons, they convert that target
molecule into a radical. So a chain reaction begins that will
propagate until two radicals meet each other and each
contributes its unpaired electron to form a covalent bond
linking the two."
-http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/ROS.html
quote:
WaiSays:Where do those external radicals come from
?
From inhaling polluted air and from consuming
prepared foods, containing damaged proteins or too much
minerals. Most damaged protein cannot easily be
decomposed by enzymes in the digestive tract. Both
decomposed- and partly-decomposed proteins are absorbed into
the lymph and the blood. And in the blood radicals and
enzymes decompose all substances that shouldn’t be there,
step by step. Decomposing these substances, very often
radicals originate. And sometimes these radicals damage
cells before they are completely decomposed.
So this breakdown process of protein is very important,
and when damaged protein is broken down, step by step, these
radicals originate because of how complicated this process
is??? What exactly makes free radicals originate from
damaged protein? Is this not a natural process for our
body?
Can anything be a radical? damaged fat? I take it
damaged protein is more of a culprit because it takes
longer/more complex to breakdown?
What gives oxidative
radicals the ability to damage cell DNA/RNA (which could cause
a mutation, thus cancer?). I understand that cancer is a
mutated cell that reproduces until death.
Thanks once
again RRM.
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RRM Administrator
Member # 2
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posted October 18, 2005 05:21 AM
quote:
So
this breakdown process of protein is very important, and
when damaged protein is broken down, step by step, these
radicals originate because of how complicated this process
is???
No, just because of the breaking down.
quote:
What
exactly makes free radicals originate from damaged protein?
Is this not a natural process for our body?
Yes, it's natural. But, there are different types of
radicals; long- or short-living (simple) ones. Toxins are
long-living, and specific toxins may bind to receptors in the
brain. Due to the breakdown / utilization of nutrients,
mostly just short-living simple radicals
originate.
quote:
Can
anything be a radical?
Anything that can be broken down; molecules (including
the clean air that we breath), but not elements, such as
minerals (potassium etc)and trace elements (selenium
etc)
quote:
damaged fat?
All fats, carbs and protein.
quote:
I
take it damaged protein is more of a culprit because it
takes longer/more complex to breakdown?
The biggest danger from damaged protein are the stable
toxins that originate due to the maillard reaction. But,
yes, molecules that are not broken down by digestive enzymes
in the digestive tract, but instead by decomposing enzymes in
the blood and lymphe, will indeed cause some damage in these
systems, and organs.
quote:
What
gives oxidative radicals the ability to damage cell DNA/RNA
(which could cause a mutation, thus cancer?)
As you pointed out, radicals may cause a chain reaction
until they meet another radical. This may happen at the
outside of a cell, going on inside the cell and into the
nucleus. Its as if the radical is a lone fighter that
tries to fight his way into the palace to kill the king. His
fighting skills are passed on to and from each inhabitant of
the palace, but come to an end if the inhabitant is an armed
guard (also a radical, or an antioxidant). Since there are
a lot of guards in the palace, chances are slim that the king
will get killed, but if these penetrations take place very
often, the king may get hurt at some point.
Toxins are
way more dangerous than such unstable radicals because they
are stable; they are 'ninja fighters' that can only be
slightly wounded by a guard, and they therefore are way more
capable in reaching the king.
quote:
I
understand that cancer is a mutated cell that reproduces
until death.
All cells reproduce until death. Normally, cells do
what they are designed for, reproducing at a normal
pace. Tumors are clusters of cells that do not function
normally, due to damgae done to their DNA/RNA (by radicals or
toxins). In malign tumors, this damage specifically has
damaged the cells capacity to inhibit their own growth,
causing these cells to produce way more of one or more growth
factors / hormones than inhibitors, accelerating their
reproduction. Thus, these malign tumors grow very fast,
overtaking normal functioning cells, which may lead to
disfunctioning organs, and death.
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nick Moderator
Member # 5
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posted October 18, 2005 11:37 AM
quote:
Yes,
it's natural. But, there are different types of radicals;
long- or short-living (simple) ones. Toxins are long-living,
and specific toxins may bind to receptors in the
brain. Due to the breakdown / utilization of nutrients,
mostly just short-living simple radicals
originate.
I see the difference between toxin and radical.
Beta-carbolines have toxic properties.
These HCA, from
the "New Substances in Prepared Food", I take it that all HCA
are bad? These HCA are those Malliard Reactant products, from
the sugars and proteins. I take it HCA has do with the
chemical make-up/arrangement of these damaged
proteins.
quote:
The
biggest danger from damaged protein are the stable toxins
that originate due to the maillard reaction. But, yes,
molecules that are not broken down by digestive enzymes in
the digestive tract, but instead by decomposing enzymes in
the blood and lymphe, will indeed cause some damage in these
systems, and organs.
Because of the radicals that originate, which are then
eventually 'caught' by a gaurd. That makes
sense.
quote:
As you
pointed out, radicals may cause a chain reaction until they
meet another radical. This may happen at the outside of a
cell, going on inside the cell and into the
nucleus.
Do you mean it starts at the outside, then progresses
to the inside then into the nucleus. Like a step by step
process?
quote:
Its as if the radical is a lone fighter that
tries to fight his way into the palace to kill the king. His
fighting skills are passed on to and from each inhabitant of
the palace, but come to an end if the inhabitant is an armed
guard (also a radical, or an antioxidant). Since there
are a lot of guards in the palace, chances are slim that the
king will get killed, but if these penetrations take place
very often, the king may get hurt at some point.
Great analogy, that makes it so much easier to
visualize! However, when you mean king, do you mean the
nucleus of a cell?
Does the palace mean that one
individual cell, or do you mean the entire body?
This
analogy seems to have a double description of how an
individual cell would respond, and how all the cells in the
body would respond as well. Does that make
sense?
quote:
Toxins
are way more dangerous than such unstable radicals because
they are stable; they are 'ninja fighters' that can only be
slightly wounded by a guard, and they therefore are way more
capable in reaching the king.
These toxins could be HCA and beta-carbolines, correct?
Which is what makes them so much more dangerous. Because they
are totally different from radicals, they are substances that
on their own are toxic.
quote:
All
cells reproduce until death. Normally, cells do what they
are designed for, reproducing at a normal pace. Tumors
are clusters of cells that do not function normally, due to
damage done to their DNA/RNA (by radicals or
toxins).
I was reading that when a radical or toxin gets to the
nucleus it damages certain genes, such as the oncogene, and
when this damage isn't repaired, it leads to abnormal cell
reproduction(mitosis). Thus leading to tumors=uncontrolled
cell division.
quote:
In malign tumors, this damage specifically
has damaged the cells capacity to inhibit their own growth,
causing these cells to produce way more of one or more
growth factors / hormones than inhibitors, accelerating
their reproduction. Thus, these malign tumors grow very
fast, overtaking normal functioning cells, which may lead to
disfunctioning organs, and death.
When these malign tumors produce one or more growth
factors/hormones, does this increase the hormone level
throughout the body, or just in those cells/tumors?
So
cancer is uncontrolled cell division that takes control over
other cells. How do these cancerous infect/takeover other
cells. By attacking their DNA?
Thanks
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RRM Administrator
Member # 2
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posted October 18, 2005 02:57 PM
quote:
Originally posted by nick: These HCA, from the
"New Substances in Prepared Food", I take it that all HCA
are bad?
No, it totally depends on their molecular structure
whether they contain toxic properties, or the property to
'just' influence receptors in the brain or other
organs.
quote:
These
HCA are those Malliard Reactant products, from the sugars
and proteins. I take it HCA has do with the chemical
make-up/arrangement of these damaged proteins.
Yes; the name HCA is specific for a group of
protein-sugar maillard products, named after their molecular
structure.
quote:
Do
you mean it starts at the outside, then progresses to the
inside then into the nucleus. Like a step by step
process?
Yes, this MAY happen, but chances are slim, since these
attackers have no will; they just randomly attack whatever may
come in their path. So, that is why you can imagine that
endogenous normal radicals are very unlikely to cause cancer,
though it is possible in theory. Even when they last long
enough, and even when they end up in the nucleus, chances are
furthermore very slim that specifically that part of the
DNA/RNA is damaged that holds the information to balance
growth hormones /factors and their inhibitors.
quote:
However, when you mean king, do you mean the
nucleus of a cell?
Hmm, good question. Maybe much more specifically: that
part of the DNA/RNA where the information about balancing
growth stimulators and inhibitors is located, since only
damage to that part may cause cancer (if 'not only injured,
but fatally injured'). Damage to 'other royals' (other parts
of the DNA/RNA) will only affect functioning of those cells
(the cell plus its 'offspring').
quote:
Does
the palace mean that one individual cell, or do you mean the
entire body?
Maybe every cell represents a kingdom, with the nucleus
being the palace, and the DNA/RNA the rooms where the royals
sleep. That part of the DNA/RNA where the information about
balancing growth stimulators/inhibitors is located, is the
king.
quote:
This
analogy seems to have a double description of how an
individual cell would respond, and how all the cells in the
body would respond as well. Does that make sense?
I'm sorry, but I don't understand. Could you be more
specific?
quote:
These
toxins could be HCA and beta-carbolines, correct?
Yes, they could (beta-carbolines are a specific group
of HCA).
quote:
I was
reading that when a radical or toxin gets to the nucleus it
damages certain genes, such as the oncogene, and when this
damage isn't repaired, it leads to abnormal cell
reproduction(mitosis). Thus leading to tumors=uncontrolled
cell division.
If a toxin reaches the nucleus (palace), it doesn't
necessarily kill one of the royals. And even if that does
happen, this doesn't have to be disastrous, unless its the
king. If another member of the royal family gets killed,
that cell may stop functioning properly (the kingdom may fall
apart), without leading to cancer (the kingdom becoming an
evil, agressive empire). With cancer, normal functioning
cells cannot compete because reproduction of the
disfunctioning cells is accelerated, due to a lack of growth
inhibitors (because that part of the DNA/RNA has been
damaged). If the damage is not repaired, those cells will
continue to reproduce at a faster pace, and they will
therefore overpower normal functioning cells.
A tumor
is not the same as uncontrolled cell division. A tumor is a
group of cells that don't function normally; they seem useless
/ out of place. If the reproduction rate is not accelerated,
it is a benign tumor, and our own protein-decomposing enzymes
may get rid of it eventually, or not. If reproduction is
accelerated, it is a malign tumor.
quote:
When
these malign tumors produce one or more growth
factors/hormones, does this increase the hormone level
throughout the body, or just in those
cells/tumors?
Every cell produces growth hormones / factors, but this
is balanced by growth inhibitors, so that growth is
controlled. Only if sufficient growth inhibitors are produced,
will reproduction be accelerated. Depending on what growth
stimulator is over-active, that tumor is named after that
growth stimulator. For example: in a prolactinoma the level
of prolactine is increased.
If the blood-prolactine
level is increased (in the above example), the cancer is
likely to be widespread already. In the first stages of cancer
an increased level of prolactine may not get noticed; it
starts in the cell, with some of it leaking outside, so that
only a large group of such cells will increase serum
prolactine level.
quote:
So
cancer is uncontrolled cell division that takes control over
other cells. How do these cancerous infect/takeover other
cells. By attacking their DNA?
They simply grow faster, 'suffocating' other cells;
taking away their nutrients / starving them. There is no 'evil
design' in cancer cells other than accelerated reproduction.
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nick Moderator
Member # 5
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posted October 18, 2005 10:37 PM
quote:
Yes,
this MAY happen, but chances are slim, since these attackers
have no will; they just randomly attack whatever may come in
their path. So, that is why you can imagine that
endogenous normal radicals are very unlikely to cause
cancer, though it is possible in theory. Even when they
last long enough, and even when they end up in the nucleus,
chances are furthermore very slim that specifically that
part of the DNA/RNA is damaged that holds the information to
balance growth hormones /factors and their
inhibitors.
But the more cooked food that you eat, more of the
'attacks' occur, the higher the probability of something
harmful occuring? Makes sense to me.
quote:
Hmm,
good question. Maybe much more specifically: that part of
the DNA/RNA where the information about balancing growth
stimulators and inhibitors is located, since only damage to
that part may cause cancer (if 'not only injured, but
fatally injured').
So when the cells are attacked by these radicals, and
they fatally injure the part that regulates
growth-stimulators/-inhibitors. Like you said the radical has
no will, so is it just a matter of chance that it hits the
growth regulation part of the DNA?
Does it take just
ONE cell to be fatally attacked which could lead to cancer
through out the body, depending on the type (aggressive, less
aggressive), as it will grow exponentially?
quote:
Damage to 'other royals' (other parts of the DNA/RNA)
will only affect functioning of those cells (the cell plus
its 'offspring').
This doesn't cause cancer, but does it cause
health-problems? I would think so.
quote:
A
tumor is not the same as uncontrolled cell division. A tumor
is a group of cells that don't function normally; they seem
useless / out of place. If the reproduction rate is not
accelerated, it is a benign tumor, and our own
protein-decomposing enzymes may get rid of it eventually, or
not. If reproduction is accelerated, it is a malign
tumor.
Do radicals orginate these tumors? or can damaging some
of the royals produce non-normal functioning cells which can
cause tumors?
quote:
In
the first stages of cancer an increased level of prolactine
may not get noticed; it starts in the cell, with some of it
leaking outside, so that only a large group of such cells
will increase serum prolactine level.
serum=measurable in the blood? much like serum
cholesterol, etc...
quote:
They
simply grow faster, 'suffocating' other cells; taking away
their nutrients / starving them. There is no 'evil design'
in cancer cells other than accelerated
reproduction.
I used to think that cancer cells were malicious and
full of evil intent, but I see the picture much clearer now.
So when a certain cancer is aggressive it makes it much harder
to combat, because they take away nutrients from other cells
and since there are more cancer cells growing, they demand
more and more of the supply for there accelerated growth rate.
I take it that the bodies' immune response isn't sufficient
(depending on the cancer), when it comes to ever-increasing
cancer cells?
I find myself looking information at this
biology site and learning more and more and connecting dots
and so on. Its very interesting how it all fits
together.
Thanks again!
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RRM Administrator
Member # 2
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posted October 19, 2005 10:59 AM
quote:
But
the more cooked food that you eat, more of the 'attacks'
occur, the higher the probability of something harmful
occuring?
Yes.
quote:
Like
you said the radical has no will, so is it just a matter of
chance that it hits the growth regulation part of the
DNA?
Yes.
quote:
Does
it take just ONE cell to be fatally attacked which could
lead to cancer through out the body, depending on the type
(aggressive, less aggressive), as it will grow
exponentially?
Yes, just one cell...
quote:
RRM: Damage to 'other royals' (other parts of
the DNA/RNA) will only affect functioning of those cells
(the cell plus its 'offspring').
quote:
Nick: This doesn't cause cancer, but does it
cause health-problems?
No, because such cells normally are decomposed, and
even when they are not, only benign tumors originate. Only
if this happens frequently (eating cooked foods regularly),
ageing of these cells is accelerated, which is indeed a health
problem.
quote:
Do
radicals orginate these tumors?
That's highly unlikely, but possible in
theory.
quote:
or
can damaging some of the royals produce non-normal
functioning cells which can cause tumors?
No, only if that part of the DNA/RNA is damaged where
the info about the balance between growth stimulation and
inhibition is located (the king).
quote:
serum=measurable in the blood? much like serum
cholesterol, etc...
Yes.
quote:
So
when a certain cancer is aggressive it makes it much harder
to combat, because they take away nutrients from other
cells
Exactly.
quote:
and
since there are more cancer cells growing, they demand more
and more of the supply for there accelerated growth rate. I
take it that the bodies' immune response isn't sufficient
(depending on the cancer), when it comes to ever-increasing
cancer cells?
Immune response is essential indeed, but I don't know
to what extend.
quote:
Thanks again!
You are welcome!
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nick Moderator
Member # 5
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posted October 23, 2005 10:13 PM
What do you
think about the beyond veg website?
You mentioned
their site in your "Genetic is a Lie" article.
They
think that fire was created 125,000 years ago, with some very
good facts and arguementation.
They also
have research on heating/cooking and the toxins they
originate.
I haven't read the whole article
though.
In that case, what are some of the other causes
of cancer besides cooked food and high levels of
radiation?
I understand that ones susceptibility to
cancer isn't genetic, but that susceptibility to cooked food
toxins definitely plays a role in the probability of
developing cancer.
Thanks
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RRM Administrator
Member # 2
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posted October 24, 2005 11:17 AM
quote:
What
do you think about the beyond veg website?
That it contains lots of good information, and some
less good.
quote:
They
think that fire was created 125,000 years ago, with some
very good facts and arguementation.
Yes, that might be. 1.6 million years ago, humans
had already fully developed in over 6 feet tall beings. 0.1
million years is not much on the scale of evolution.
By nature, we have the capacity to neutralize some of
the toxins present in smoke from (forrest)fires, which are
partly the same as in cigarette smoke and cooked foods. So,
yes, we can neutralize such toxins to some degree, by nature,
that doesn't mean we have adapted to the toxins in cooked
foods. We still are susceptible to those toxins, as they
are also present in cigarette smoke; smoking increases lung
cancer risk.
quote:
what
are some of the other causes of cancer besides cooked food
and high levels of radiation?
Air pollution, (passive) smoking, dairy products,
consuming too much hard fiber (coloncancer), Phtalates from
soft plastic, excessive sunlight exposure (skin cancer).
Probably miss a few.
quote:
I
understand that ones susceptibility to cancer isn't genetic,
but that susceptibility to cooked food toxins definitely
plays a role in the probability of developing
cancer.
Yes; to what extend specific enzymes can neutralize
such toxins is genetic, though many toxins cannot be
neutralized by these enzymes.
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Oscar Moderator
Member # 14
|
posted October 25, 2005 11:28 AM
I'm
wondering about excessive sunlight causing skin cancer. Does
this mean that people around the equator have more skin cancer
than people further away from it? Or do they have more
protection against the sunlight? And does diet have an
influence on that protective aspect and the susceptibility to
skin cancer?
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RRM Administrator
Member # 2
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posted October 25, 2005 11:41 AM
quote:
Originally posted by Oscar: I'm wondering about
excessive sunlight causing skin cancer. Does this mean that
people around the equator have more skin cancer than people
further away from it? Or do they have more protection
against the sunlight?
People around the equator naturally have a darker skin,
which protects them against the sun indeed.
quote:
And
does diet have an influence on that protective aspect and
the susceptibility to skin cancer?
I don't think so; it's more that the darker your skin
(by nature), the better you are protected. Though it might
be that excessive vitamin E increases skincancer risk. http://www.3.waisays.com/
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nick Moderator
Member # 5
|
posted October 25, 2005 02:14 PM
quote:
Tumors
are clusters of cells that do not function normally, due to
damgae done to their DNA/RNA (by radicals or toxins). In
malign tumors, this damage specifically has damaged the
cells capacity to inhibit their own growth, causing these
cells to produce way more of one or more growth factors /
hormones than inhibitors, accelerating their reproduction.
So these benign tumors, there DNA/RNA has been damaged
in a different area than malign tumors (reproduction rate).
Ok, that makes sense!
From the "Milk Causes Cancer Too"
quote:
In
cystic breasts, breast-cells are more sensitive to
substances stimulating cell-fission, and therefore
cell-reproduction-rate is higher.
What exactly is a cystic breast? Does cell-fission mean
reproduction? Why are cystic breasts more sensitive to
substances that stimulate cell-fission?
quote:
And
by taking testosterone, prostate- and muscle-cells are more
stimulated to reproduce. In tissues where reproduction-rate
is increased, growth of mutated cells is stimulated as well,
increasing cancer-risk.
Who would be taking testorone? Wieght Lifters?
Athletes? People with certain conditions? Are we talking about
a higher than average intake of testorone? Which would
increase the testosterone level above what is normal?
quote:
By
absorbing external growth factors, tumors can originate. And
tumors can become malignant when they, due to a mutation,
start producing more growth factors, stimulating their own
reproduction.
Does the body increase it own levels of growth
inhibitors to counteract this influx of external growth
factors? How do external growth factors orginate tumors? By
damaging their DNA/RNA? much like radicals?
In that
case, external growth factors can cause cancer indirectly?
(by influencing cell growth of healthy and mutated
cell?)
From the "Foods Causing Cancer"
article
quote:
Phyto-estrogens are 'weak' estrogens, and can
replace common (powerful) estrogens. And because excessive
estrogen can cause breast cancer, these phyto-estrogens are
regarded as 'good' substances. Soya contains most
phyto-estrogen.
So these 'weak' estrogens occupy the same receptors as
endogenous estrogen would, therefore decreasing the amount of
estrogen created by the body?
Which could lead to
infertility as mentioned in the article.
quote:
To
prevent cancer caused by estrogens, you should not use
hormonal contraceptives
Don't they decrease the level of estrogen? So how they
could cause cancer?
From the "New Substances in
Prepared Food" article
quote:
Some
HCA in prepared food are mutagenic. DNA-damage increases
linearly with intake of HCA. How cancerous HCA are is
partly dependent on how much nitrogen they contain.
Salt, protein and nitrite (from vegetables) can supply
nitrogen to react upon HCA. And nitrosated HCA are even more
cancerous. Some of the most widespread mutagenic HCA in
prepared foods are :
pyridoindole (80)
(amino-gamma-carboline) 2-amino-9H-pyrido(2,3-b)indole
(81)
(amino-alpha-carboline) 2-amino-3-methyl-9H-pyrido(2,3-b)
(82) 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole
(83) 3-amino-1-methyl-5H-pyrido(4,3-b)indole
(84) 1-methyl-3-carbonyl-1,2,3,4-tetrahydro-beta-carboline
(85). 4-aminobiphenyl (86) 4,4'-methylenedianiline
(87) 3,2'-dimethyl-4-aminobiphenyl
(88) 1,2-dimethylhydrazine (89) phenyl-hydroxylamine
(90) O-acetyl-N-(5-phenyl-2-pyridyl)-hydroxylamine
(91) 2-amino-3-methylimidazo(4,5-f)quinoline
(92) 2-amino-3-methylimidazo(4,5-f)quinoxaline
(93) 2-amino-3,4-dimethylimidazo(4,5-f)quinoline
(94) 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
(95) 2-amino-3,4,8-trimethylimidazo(4,5-b)pyridine
(96) 2-amino-3,4,8-trimethylimidazo(4,5-f)quinoxaline
(97) 2-amino-3,7,8-trimethylimidazo(4,5-f)-quinoxaline
(98) 2-amino-n,n,n-trimethylimidazo-pyridine
(99) 2-amino-n,n-dimethylimidazopyridine
(100) 2-amino-4-hydroxymethyl-3,8-dimethylimidazo-(4,5-g)-quinoxaline
(101) 2-amino-1,7,9-trimethylimidazo-(4,5-g)-quinoxaline
(101) 2-amino-1-methyl-6-phenylimidazo-(4,5-b)-pyridine
(102)
How do carcinogens attack the DNA/RNA? Do they work
like oxidative radicals? Mutagenic means the ability to cause
cancer, so when these substances are broken-down, radicals
orginate thus increasing cancer risk, or do these toxins
directly attack the cell DNA/RNA?
Thanks!
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Oscar Moderator
Member # 14
|
posted October 26, 2005 05:42 AM
quote:
I don't
think so; it's more that the darker your skin (by nature),
the better you are protected.
Right. But because of the diet, I feel my skin change
(as we probably all feel), so I wonder if that change also
means the skin becomes more resistant against all kinds of
harmful influences? And thus also sunlight?
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RRM Administrator
Member # 2
|
posted October 26, 2005 10:44 AM
quote:
Originally posted by nick: What exactly is a
cystic breast?
Breasts that swell up (in the hormonal cycle, or due to
getting pregnant).
quote:
Does
cell-fission mean reproduction?
Fission is part of the replication process indeed.
(reproduction may not be the correct term)
quote:
Why
are cystic breasts more sensitive to substances that
stimulate cell-fission?
Because their receptor sensitivity to such stimulating
substances has been increased because they are supposed to be
cystic at that time; when pregnant for example.
quote:
Who
would be taking testorone? Weight Lifters? Athletes? People
with certain conditions?
Indeed.
quote:
Are we
talking about a higher than average intake of testorone?
Which would increase the testosterone level above what is
normal?
Any intake of testosterone may increase serum
testosterone above normal.
quote:
Does
the body increase it own levels of growth inhibitors to
counteract this influx of external growth
factors?
Yes.
quote:
How
do external growth factors orginate tumors? By damaging
their DNA/RNA? much like radicals?
No, by stimulating growth where that shouldn't happen;
they may stimulate growth of cells that (due to a mutation)
have become more sensitive to such a stimulating influence, to
such an extend that they grow faster than our own defense
system can break them down.
quote:
In
that case, external growth factors can cause cancer
indirectly? (by influencing cell growth of healthy and
mutated cell?)
Yes.
quote:
So
these 'weak' estrogens occupy the same receptors as
endogenous estrogen would, therefore decreasing the amount
of estrogen created by the body?
Not the amount created, but the actual level in the
blood and especially total estrogen activity.
quote:
To
prevent cancer caused by estrogens, you should not use
hormonal contraceptives
quote:
Don't
they decrease the level of estrogen? So how they could cause
cancer?
Some increase estrogen level. all contraceptives
dominate / overpower our natural hormone
metabolism.
quote:
How
do carcinogens attack the DNA/RNA? Do they work like
oxidative radicals?
They have direct toxic (damaging) properties, directly
damaging cells / cellDNA
quote:
Mutagenic means the ability to cause
cancer,
Mutagenic means the ability to cause mutations (to cell
DNA/RNA).
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RRM Administrator
Member # 2
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posted October 26, 2005 10:46 AM
quote:
Originally posted by Oscar: I wonder if that
change also means the skin becomes more resistant against
all kinds of harmful influences? And thus also
sunlight?
I have no idea. A more 'pumped up' skin (retaining
more water) better protects you against bruises though. Your
skin is not just softer now, but also a bit more sensitive and
vulnerable.
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Oscar Moderator
Member # 14
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posted October 26, 2005 06:07 PM
Really?
Hmmm, I seem to feel that, although my skin is softer, it also
feels thicker (my nails too) and less vulnerable. But I
haven't yet bruised myself, so I have to wait and see I
guess...
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RRM Administrator
Member # 2
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posted October 27, 2005 03:12 PM
When you
want to pop a blackhead, you will find out that applying as
much pressure as you used to do, you will now cause more
damage to the skin (resulting in a small wound or
redness)
Maybe you feel that your skin is thicker now
because you no longer apply chemicals to your skin that make
your skin peel? (so that your skin has regained its natural
thickness?)
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Oscar Moderator
Member # 14
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posted October 27, 2005 04:51 PM
Hmm, I
haven't noticed more 'popping' damage yet, but you could be
right about the chemical thing.
On a totally different note: I was wondering what is
considered to be "a lot" of fiber, when combining foods?
Avocado has 6% fiber, so can it be combined with tomato and
cucumber, or even fish, or should it be eaten alone?
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RRM Administrator
Member # 2
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posted October 28, 2005 12:11 PM
You cant
just put a number on it, because it depends whether you talk
about overal fiber intake, or about food-combining. Maybe its
better to see "not too much fiber" advice as a general one,
and look into food combining more specifically. Avocado with
egg yolks is fine, for example, but avocado with raw fish
might be less perfect somehow. And...it also differs
individually very much...
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Oscar Moderator
Member # 14
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posted October 28, 2005 05:41 PM
Ah, thanks!
I guess I'll just experiment a bit...
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RRM Administrator
Member # 2
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posted October 30, 2005 01:34 PM
Yes, that's
the best way!
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